ODCs

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3 OMIM references -
4 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
9 signs/symptoms

Autosomal dominant macrothrombocytopenia

Legg-CalvÃ©-Perthes disease


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ITGA2B	(0.85)	COL2A1

Citations in the biomedical literature:

Autosomal dominant macrothrombocytopenia		Legg-CalvÃ©-Perthes disease
	Synonym(s): (no synonyms)		Synonym(s): - Aseptic necrosis of the capital femoral epiphysis - Osteochondritis of the capital femoral epiphysis - Osteochondrosis of the capital femoral epiphysis - Perthes disease

	Classification (Orphanet): - Rare genetic disease - Rare hematologic disease		Classification (Orphanet): - Rare bone disease - Rare genetic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: - Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: normal Type of inheritance: autosomal dominant

	External references: 3 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Legg-CalvÃ©-Perthes disease
	Very frequent - Abnormal dentition / dental position / implantation / unerupted / dental ankylosis - Articular / joint pain / arthralgia - Cartilage destruction / chondrolysis - Delayed bone age - Joint / articular deformation - Muscle hypotrophy / atrophy / dystrophy / agenesis / amyotrophy - Osteonecrosis / bone infarction - Polygenic / multifactorial inheritance - Short stature / dwarfism / nanism
Autosomal dominant macrothrombocytopenia
(no data available)